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Publications & Presentations


Inside Vanilla

Daphna Havkin-Frenkel, James French, Fulya Pak and Chaim Frenkel, Perfumer & Flavorist

Pushing for Sustainability with a Social Impact

Daphna Havkin-Frenkel & Juan Guardado, The World of Food Ingredients


​The Root Market Problems with Vanilla

Daphna Havkin-Frenkel. Food Ingredients First.


Biotechnology in Flavor Production

Daphna Havkin-Frenkel and Nativ Dudai


Vanilla Around The World: Challenges and New Opportunities - 2014

Daphna Havkin-Frenkel.  Society of Flavor Chemists.

Recently cited in:

4D food printing technology: Structural changes to culinary art and beyond

Poornima Singh, Vinay Kumar Pandey, Anjali Tripathi, Rahul Singh, Tarun Singh Shri Net, Seema Ramniwas, R. Pandiselvam


A deep transcriptomic analysis of pod development in the vanilla orchid (Vanilla planifolia)

Rao, X., Krom, N., Tang, Y., Widiez, T., Havkin-Frenkel, D., Belanger, F.C., Dixon, R.A., and Chen, F. (2014). BMC genomics in press

Plant Cell and Tissue Culture for the Production of Food Ingredients

Edited by T-J. Fu, G. Singh, and W. Curtis. 2012

A polymer of caffeyl alcohol in plant seeds -

Chen, F., Tobimatsu, Y., Havkin-Frenkel, D., Dixon, R.A., and Ralph, J. (2012). 

Proceedings of the National Academy of Sciences USA 109, 1772-1777 


Effective postharvest processing turns herbal waste into beneficial  product – the case of oregano - 2011

Daphna Havkin-Frenkel, Nativ Dudai and Hans van der Mheen


Functional characterization of two new members of the caffeoyl CoA O-methyltransferase-like gene family
from Vanilla planifolia reveals a new class of plastid-localized O-methyltransferases - 2011

Thomas Widiez, Thomas G. Hartman, Nativ Dudai, Qing Yan, Michael Lawton, Daphna Havkin-Frenkel,  Faith C. Belanger


Handbook of Vanilla Science and Technology - 2011
Edited by Daphna Havkin-Frenkel and Faith Belanger
Provides a comprehensive overview of the science and technology used in the production and supply chain of vanilla products.


Biotechnology Production of Vanillin  - 2008

Daphna Havkin-Frenkel, IFT, New Orleans 


Biotechnology in Flavor Production - 2008

Edited by Daphna Havkin-Frenkel and Faith Belanger


II International Symposium on Natural Preservatives in Food, Feed, and Cosmetics - 2008
ISHS Acta Horticulturae 778
Edited by Daphna Havkin-Frenkel, Nativ Dudai, Hans van der Mheen
Discoloration of Oregano Post-Distillation Left-Over Leaf Extract
D. Yi Jin Booth, A. Sinha, K.E. Galasso, and D. Havkin-Frenkel


Application of Plant Metabolic Engineering - 2007
Edited by R. Verpoorte, A.W. Alfermann, T.S. Johnson
Application of Metabolic Engineering to Vanillin Biosynthetic Pathways in Vanilla planifolia
Daphna Havkin-Frenkel and Faith Belanger


Vanilla: The Food of the Gods
Daphna Havkin-Frenkel

Agro Food Industry Hi-tech, February/March 2007


Post Harvest Handling and Storage of Cured Vanilla Beans
Daphna Havkin-Frenkel and Chaim Frenkel


Evolution of novel O-methyltransferases from the Vanilla planifolia caffeic acid O-methyltransferase

Huaijun Michael Li, David Rotter, Thomas G. Hartman, Fulya E. Pak, Daphna Havkin-Frenkel and Faith C. Belanger

Plant Molecular Biology - 2006


Proceedings of the First International Symposium on Natural Preservatives in Food Systems 2006
Edited by Dr. Daphna Havkin-Frenkel, Dr. Nativ Dudai, and Dr. Chaim Frenkel

Dr. Daphna Havkin-Frenkel is an editor for the Proceedings of the First International Symposium on Natural Preservatives in Food Systems. The book has been published by ISHS and is now available. For more details, or to order a copy of the proceedings, go to


Natural Preseravtives in Oregano
Dudai, N.; Segev, D.; Havkin-Frenkel, D.; Eshel, A. (2006) Genetic variation of phenolic compounds content, essential oil composition and anti oxidative activity in Israel-grown Mentha longifolia L.  Published in Proceedings of the First International Symposium on Natural Preservatives in Food Systems, by ISHS


The Physics and Chemistry of Vanillin Frenkel, C., and  Havkin-Frenkel, D.  Perfumer and Flavorist. Vol. 31, pg. 28-36; 2006


Daphna Havkin-Frenkel is featured in Chemical and Engineering News Magazine - 2006


Vanilla, The Proceeding of the First International Congress - 2003


The State of Vanilla
Perfumer and Flavorist, November/December 2005


Patent on the Extraction of useful component from post distillation plant material: -2005


An article by Dr. Daphna Havkin-Frenkel et. al. appears in the May issue of Perfumer and Flavorist


Chemistry and Physics of Vanillin in Personal Care Applications.

Chaim Frenkel
Symposium on High Function Naturals, New York, NY April 13, 2004


A hairy tissue produces vanillin.
Israel Journal of Plant Sciences Vol. 51 2003 pp. 157–159.
A unique secretory tissue produces the most important flavoring agent. Vanillin accumulates in the secretion around the seeds in the mature fruit of the vanilla orchid. A unique secretory tissue that is composed of closely packed unicellular hairs is located in the three gaps between the placentas along the central fruit cavity. These cells contain enzymes that are involved in vanillin biosyntheis and seem to be responsible for vanillin secretion.


Characterization of a multifunctional methyltransferase from the orchid Vanilla planifolia

F. E. Pak · S. Gropper · W. D. Dai · D. Havkin-Frenkel · F. C. Belanger - 2003


Patent on the production of vanillin -2003


Interrelation of curing and botany in Vanilla (Vanilla planifolia) bean. 2003


Unusual 4-hydroxybenzaldehyde synthase activity from tissue cultures of the vanilla orchid Vanilla planifolia. 3.Podstolski, A., Havkin-Frenkel, D., Malinowski, J., Blount, J.W., Kourteva, G., and Dixon, R.A. (2002).  Phytochemistry 61, 611-620.

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